To manufacture items you need materials and a blueprint. Let's stick to the simpler case: T1 manufacture. In this case the blueprints are originated from NPCs who sell it in large quantities. However these blueprints are not researched. Most of them have 10% wastage factor, so you need 10% more materials to manufacture than you'd get by instantly reprocess the product. You can improve the material efficiency of the blueprint by bringing it to a station with material research slots and... 
Thanks to the ingenious design of CCP, the material research slots are clogged all around empire and even in most nullsec. The reason for that is the research costs are trivial while the value increase of the blueprint is relevant. For example a titan takes about 60B materials, so the 10% wastage factor means 6B waste. Research it to just 1 ME and it drops to 3B. Research to 2 and you save another billion. While you have to pay some fee to the NPCs running the station, it's usually less than a million. CCP managed to skip on this great option to have an ISK sink. Since research is nearly free and needs very little effort, no wonder that lot of people mass-produce researched BPOs, clogging the system.
If you aren't a professional manufacturer and just want to produce a few odd items, you are better off skipping this phase and buy a blueprint copy from contracts. Copies are made from the original and have limited usages. If you do some limited manufacturing, like making ammo for yourself from the loot you reprocessed, you can buy researched blueprint originals. They are expensive but you get them instantly.
However if you plan to run serious industry (or want some passive income), you'll need the research. To compensate for the slow waiting time you can only do one thing: having more research slots. This way the different researches don't have to wait for each other. One character can do one research without skills, that can be increased to 11 with Advanced Laboratory Operation 5, but since it's a 8x skills, it's better to settle with lvl4 and 10 slots. However there are 3 character slots in every account and you aren't bound to one account. Generally if you want to research something and you have no slots, you need another researcher. Since the waiting time is long (usually more than a month per job) even full time combat characters can research, they can do the trip to empire once in two months.
What else you need? Covops frigate (or T3). The highsec slots are usually 30+ day long, the lowsec ones on the other hand are around 8-15, significant time decrease.
Important: research - exactly because it is "free" - is not a money print. If you buy some BPO and research it, it won't sell for huge profit automatically. There are examples for good sales and there are counterexamples. For example Nyx blueprint original is sold for 18B by the NPCs. Yet in contracts with even significant research (like 5ME 1PE) you can buy them for 16B. Why? Because people bought it, researched it and couldn't sell it. Now they have to suck it up and sell the damn thing at loss. So always check contracts before you start researching!
You can set up a POS in an altcorp in highsec but I don't think it worth the effort of fueling and dealing with wardeccers. The NPC slots are free and you can cut the research time by getting multiple jobs running (waiting) in the same time.
You can also research production efficiency (manufacturing speed) but there are usually empty slots for that even in highsec.
Recently there are many JF kills. I did not list them as "idiot" deaths as they must have been in lowsec and must be full off goodies. But I'm more and more inclined to include them when I see things like this I have doubts. A single T1 cruiser shouldn't be able to do this. Either cyno only to docking rings or have an ECM alt protecting the freighter.
Thanks to the ingenious design of CCP, the material research slots are clogged all around empire and even in most nullsec. The reason for that is the research costs are trivial while the value increase of the blueprint is relevant. For example a titan takes about 60B materials, so the 10% wastage factor means 6B waste. Research it to just 1 ME and it drops to 3B. Research to 2 and you save another billion. While you have to pay some fee to the NPCs running the station, it's usually less than a million. CCP managed to skip on this great option to have an ISK sink. Since research is nearly free and needs very little effort, no wonder that lot of people mass-produce researched BPOs, clogging the system.
If you aren't a professional manufacturer and just want to produce a few odd items, you are better off skipping this phase and buy a blueprint copy from contracts. Copies are made from the original and have limited usages. If you do some limited manufacturing, like making ammo for yourself from the loot you reprocessed, you can buy researched blueprint originals. They are expensive but you get them instantly.
However if you plan to run serious industry (or want some passive income), you'll need the research. To compensate for the slow waiting time you can only do one thing: having more research slots. This way the different researches don't have to wait for each other. One character can do one research without skills, that can be increased to 11 with Advanced Laboratory Operation 5, but since it's a 8x skills, it's better to settle with lvl4 and 10 slots. However there are 3 character slots in every account and you aren't bound to one account. Generally if you want to research something and you have no slots, you need another researcher. Since the waiting time is long (usually more than a month per job) even full time combat characters can research, they can do the trip to empire once in two months.
What else you need? Covops frigate (or T3). The highsec slots are usually 30+ day long, the lowsec ones on the other hand are around 8-15, significant time decrease.
Important: research - exactly because it is "free" - is not a money print. If you buy some BPO and research it, it won't sell for huge profit automatically. There are examples for good sales and there are counterexamples. For example Nyx blueprint original is sold for 18B by the NPCs. Yet in contracts with even significant research (like 5ME 1PE) you can buy them for 16B. Why? Because people bought it, researched it and couldn't sell it. Now they have to suck it up and sell the damn thing at loss. So always check contracts before you start researching!
You can set up a POS in an altcorp in highsec but I don't think it worth the effort of fueling and dealing with wardeccers. The NPC slots are free and you can cut the research time by getting multiple jobs running (waiting) in the same time.
You can also research production efficiency (manufacturing speed) but there are usually empty slots for that even in highsec.
Recently there are many JF kills. I did not list them as "idiot" deaths as they must have been in lowsec and must be full off goodies. But I'm more and more inclined to include them when I see things like this I have doubts. A single T1 cruiser shouldn't be able to do this. Either cyno only to docking rings or have an ECM alt protecting the freighter.
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